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Ferrous iron predominantly contributes to the cellular labile iron pool (LIP), participating in key metabolic reactions but also toxic reactions that can lead to oxidative stress and eventually cell death

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For instance, Morin (2,3,4,5,7-pentahydroxyflavone), found in figs, apples, guava leaves, onions, tea and grains, is recognized for its potential in treating gouty arthritis

The homogenate was filtered through a 100-M cell strainer and centrifuged at 1,000 g for 10 min at 4 C, then the nuclear pellet was washed once in nucleus preparation buffer followed by resuspension in PBS with 1% BSA and 0.2 U l Roche Protector RNase inhibitor

Third, dementia diagnoses are usually made in a secondary care setting, so dementia incidence in primary care could have been delayed or missed