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barbarum polysaccharides (LBPs) have been extensively studied for their multifaceted biological functions, which include antioxidant and anticancer activities, neuroprotective effects, and immune-regulating properties

In contrast to other mammals, humans and other primates lack a functional uricase enzyme, and can only break purines down into uric acid

FA also downregulates basement membrane components like fibronectin and collagen IV, reducing permeability, and promotes autophagy and survival pathways in retinal pigment epithelium cells

For LIC sorting, cells were stained with the following antibodies: anti-mouse CD45.1-PerCP/Cyanine5.5 (eBioscience), anti-mouse CD45.2-Brilliant Violet 510 (Biolegend), anti-c-Kit-PE/Cyanine7, and anti-Mac-1-Brilliant Violet 605 (eBioscience)

Indeed, both mRNA and protein levels were reduced in keratinocytes retrotransduced with the high-risk HPV16E6 compared to the control (Scalise et al., 2012)