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In summary, enhancing mitochondrial biogenesis through gene therapy can be achieved either by delivering genes like PGC-1 and TFAM via AAV, or by regulating the expression of relevant factors in monocytes through preoperative ex vivo lentiviral transfectionboth contributing to preconditioning for elective surgeries

PLoS ONE 16 , e0260797 (2021)

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More Energy : The B vitamins and amino acids boost your energy, so you can stay active

et al., Hijov, 2025)