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Statistical analysis Statistical analysis was done using one tailed students t-test for pair wise comparison or ANOVA followed by post-hoc Tukey test for multiple sample comparisons

Diabetes Care 2019;42:227281

The key residues in both GSH_a and GSH_b binding modes are located in the C1 region (N259 and E255), it is evident that for GSH, the C1 region of mTYR is the critical binding area

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