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A significant influx of undigested proteins into the distal intestine as a result of impaired protein absorption encourages the overgrowth of proteolytic bacteria (Sorensen, 1965), which in turn causes an increase in protein fermentation clinically manifesting in protein-energy wasting, cardiovascular diseases, neurological syndromes, and CKD progression (Figure 3)

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The aging process of the musculoskeletal system can be even more accelerated by the presence of other conditions and/or diseases, such as insulin resistance, diabetes, obesity, and chronic inflammation ( There is wide evidence about the contribution of exercise, mainly strength and resistance training, in slowing the aging process of the musculoskeletal system

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For all these reasons, health insurance denials of Foundayo and other GLP-1 medications can be devastating