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Ethics declarations Ethical approval The study was conducted in accordance with the Declaration of Helsinki, and approved by the Bioethics Committee of the Medical University of Bialystok (Resolution No

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Although the conclusions from this study are limited to neuronal cells in vitro, the mechanism of selective splicing of SS4 by neurexins in a physiological setting needs to be investigated by experiments that truly mimic neuronal activity to clarify its biological significance [81]

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However, in contrast to DENV, SARS, and MERS, CoVs infect predominantly the respiratory epithelium, not macrophages which actually expresses the FcR receptors