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Research has highlighted its effects on body weight, glucose metabolism, hepatic fat reduction, and energy expenditure, with the glucagon component adding a thermogenic dimension that distinguishes it from earlier single- and dual-agonist compounds

GLP-1 medications can also promote mild dehydration through reduced appetite and increased satiety, which naturally decreases fluid intake

From week 9 onward, the dose can increase by 2.5 mg increments every four weeks based on clinical response and tolerability

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