While the molecular consequences of cyanide exposure and its role in arresting the electron transport chain during aerobic respiration have been extensively studied, the effects of long-term and chronic exposure to sub-lethal toxicity as observed in those residing in konzo-prone regions are less understood 8
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The precise mechanisms of PCs remain unclear, necessitating further investigation into their molecular pathways
As neuroscience, AI, and digital health continue to evolve, could sleep become one of healthcare's most valuable biomarkers for understanding long-term brain health
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After overnight centrifugation, the band containing the nozzles was collected using a gradient fractionator (Labconco Auto Densi-Flow), dialyzed against Tris buffer, and the nozzles were either collected by centrifugation (1 h at 366,000 g ) or further purified using 30 ml gradients of 10-40% sucrose (wt/wt)