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Additionally, the nasal mucosas rapid mucociliary clearance (1015 min) limits the residence time of the drugs and absorption efficiency (Riese et al., 2014)

Safety evaluation To analyze whether different treatment methods are toxic to rats, we examined the histological changes in the heart, liver, spleen, lungs and kidney tissues and the blood routine and blood biochemical indicators related to liver and kidney function of different groups of rats at 16 weeks

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Final thoughts Cartalax represents a unique Russian bioregulator approach to joint health - targeting cartilage tissue specifically through gene regulation in chondrocytes rather than systemic healing like BPC-157 or TB-500

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Choosing one over the other depends entirely on the objective of the study