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Research on brain-derived neurotrophic factors in humans and animals has demonstrated that short episodes of exercise enhance neuronal function, brain vascularization, and neuronal synthesis by increasing levels of derived neurotrophic factors, hence fostering improved mood and enhanced cognition (573)

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Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS (1998) Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers