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Based on an analysis of 68 RCTs encompassing 60,720 participants, Shihab et al

They should be viewed as complementary lifestyle strategies rather than direct substitutes for pharmacotherapy when medication is clinically indicated

Both GLP-1RAs and tirzepatide demonstrated efficacy in improving circulatory lipid profiles in the large clinical trials (199, 200)

It also includes GLP-1 companion products used during care

They identify an inflammatory phenotype in WAT nearby PsA affected joints, such as Hoffa's fat pad and areas around the heel, elbow, tendons, and bursae [3335]