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doi: 10.1542/peds.2010-0433 335 SecherTKassemSBenamarMBernardIBouryMBarreauFet al

Increased blood flow means that more oxygen can be transported to the muscles, fatigue onset is delayed, and overall endurance increases

Epub 2022 Apr 12

L-carnitine plays a vital role in the -oxidation of long chain fatty acids (LCFAs) to produce energy by transporting LCFAs from the cytosol into the mitochondrial matrix, and can modulate the ratio of acetyl-CoA/CoA 3,4

However, none of these associations remained significant after correction for multiple comparisons

Consequently, once-daily subcutaneous administration of liraglutide 3.0 mg was developed for the treatment of obesity [21] and once-weekly subcutaneous administration of semaglutide 2.4 mg is currently being investigated in phase III trials for this indication [22]