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Methimazole Methimazole usually is the drug of choice in nonpregnant patients because of its lower cost, longer half-life, and lower incidence of hematologic side effects

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As such, further studies should explore whether the beneficial effects observed in PsO and early PsA could be replicated in other autoimmune disorders, providing broader therapeutic benefits across this category of diseases

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The importance of K10 P lipidation receives the support of our structure-activity relationship study where peptide 20 without K10 P lipidation reduced the receptor-mediated cAMP accumulation by 1,288-fold and 759-fold for GIPR and GCGR in the presence of 0.1% bovine serum albumin (BSA), respectively, but inappreciably influenced that of GLP-1R (Fig

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