Recent reviews (PMID 38980576, PMID 41966639, PMID 41490200) compile contemporary framings
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Partially Hydrolyzed Poly(2-alkyl/aryl-2-oxazoline)s as Thermal Latent Curing Agents: Effect of Composition and Pendant Groups on Curing Behavior
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The IR usually progresses in silence and manifests clinically years after being present in the form of hyperglycemia, favoring atherogenesis and plaque progression in a curvilinear relationship with vascular disease, even in the absence of hyperglycemia ( 2 O 2 and O 2 activate stress-sensitive serine/threonine kinases such as JNK, IKK, and PKC, which phosphorylate IRS-1 at inhibitory serine residues (Ser307, Ser612), disrupting its interaction with the insulin receptor and promoting proteasomal degradation (Roden et al., 2017)