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Individuals with an intact blood-brain barrier (BBB) are usually protected from higher dietary intake of free glutamate due to saturation of the glutamate transporter at the BBB, thereby limiting the amount of glutamate able to access the CNS (64)

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Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects

doi: 10.1007/s11356-016-8048-4 20 BhantanaP.RanaM

1 A number of studies have shown abnormalities in the autism brain, including the prefrontal cortex, temporal lobe, amygdala and cerebellum, as well as differences in total brain volume and growth trajectories