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Current recommendations include year-round protection from internal and external parasites using an appropriate preventative medication, even during winter and for indoor-only pets

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GLP-1 RAs suppress NLRP3 inflammasome activation through multiple mechanisms: inhibition of priming signals via reduced NF-B activity, attenuation of reactive oxygen species generation through enhanced mitochondrial function, induction of autophagy that removes damaged mitochondria serving as inflammasome triggers, and direct interference with NLRP3-ASC interaction through PKA-mediated phosphorylation [38,39]

Vascular dementia is caused by damage to blood vessels supplying the brain, often due to atherosclerotic cardiovascular disease