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The FDA approved Foundayo (orforglipron) in April 2026 as the first oral GLP-1 weight loss medication that can be taken with food at any time of day

If you find yourself with significant side effects 24-48 hours after each injection, adjusting the time of day can sometimes shift the peak to a more convenient window

signs of thyroid dysfunction (significant fatigue, palpitations, heat intolerance)

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