Chondroprotective potential of AOD9604 in cartilage degradation models. Arthritis Res Ther
Reduced Fat Storage (Anti-Lipogenesis) 2
Typically 2.8 mg per day (2 mg GHK-Cu plus 0.4 mg each of BPC-157 and TB-4)
Reported applications include NNMT enzyme inhibition assays measuring 1-methylnicotinamide formation or S-adenosylhomocysteine release, intracellular target-engagement assays in differentiated 3T3-L1 adipocytes where 5-Amino-1MQ reduced intracellular 1-methylnicotinamide with an EC near 2.3 M (Neelakantan et al., Biochem Pharmacol, 2018), membrane permeability and Caco-2 transport characterisation, methyltransferase selectivity panels covering COMT, DNMT1 and PRMT3, and rodent studies of NNMT inhibition in adipose tissue and liver following the antisense knockdown work of Kraus and colleagues (Nature, 2014)
Chronic stress elevates cortisol, which promotes fat storage particularly in abdominal areas, exactly where many people want to lose fat
Some people choose injections for energy support, but its always best to speak with a healthcare professional to ensure its safe and appropriate for you
