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It is a fundamental challenge to the framing of GLP-1 medications as weight loss drugs whose cardiovascular benefits are a downstream consequence of a lighter body

Fatigue : Some users may experience tiredness, particularly during the initial weeks of treatment

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Song W, et al

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Beyond the demonstrated efficacy and benefits of the dual GLP-1/GIP receptor agonist tirzepatide, on the horizon is the question of whether a triple agonist targeting all three receptors (GLP-1/GIP/glucagon) may yield even more efficacious weight loss and glycemic control