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Description

Tirzepatide is a 39amino acid dual incretin receptor agonist that activates both GLP1 and GIP receptors, enhancing glucosedependent insulin secretion, suppressing glucagon, slowing gastric emptying, and reducing appetite [1] [2]

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Consult specific drug guidelines

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GLP-1 (S) and Insulin Sensitivity: A Clinical Perspective

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Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter

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This leads to a decrease in heart rate and dilation of blood vessels, ultimately lowering blood pressure

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