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GLP-1, or glucagon-like peptide-1, is a hormone released in the intestines in response to food intake

Side effects may be more prominent during treatment initiation or dose escalation

Longuet C, et al

Role of Behavioral Interventions in the Management of Obesity

You know exactly where you will be at any given week

An Evidence-Based Perspective Key Points GLP-1 medications are safe from a psychiatric perspective and dont increase risk of depression or suicidality These medications improve mental health-related quality of life and eating behaviors beyond their effects on weight Lower doses combined with comprehensive psychological and lifestyle support produce excellent results with minimal side effects GLP-1s reduce inflammation, which directly benefits mood and neurotransmitter function Psychiatrists are well-positioned to prescribe GLP-1s as part of integrated metabolic-psychiatric care I want to address a question that comes up constantly in psychiatric circles right now