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However, pharmacodynamic interactions are a concern tesamorelin can raise blood glucose by reducing insulin sensitivity, whilst retatrutide lowers blood glucose, potentially creating unpredictable glycaemic effects

These arent well studied, and I advise against them, says Rao

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, Evaluating the Rates of Pancreatitis and Pancreatic Cancer Among GLP-1 Receptor Agonists: A Systematic Review and Meta-Analysis of Randomised Controlled Trials, Endocrinol