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Otezla (Apremilast), an Oral PDE-4 Inhibitor, Receives FDA Approval for the Treatment of Patients with Active Psoriatic Arthritis and Plaque Psoriasis

It is one of four components in the KLOW blend, present at 10mg per vial

doi: 10.3390/nu2030299

When it is deficient, it can cause folic acid deficiency, which can lead to DNA synthesis obstacles and affect the development and maturation of red blood cells

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While management of the underlying cause of the peripheral neuropathy (if applicable) is essential, treatment of the peripheral neuropathy itself includes combination of oral medication, prescription creams, physical therapy, and regenerative medicine