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Gene silencing using siRNA and Western blot protocols are described in the Supplemental Methods, as is the use of streptavidin affinity pull-down of biotinylated peptides and MS

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Back Labhart, A (1978) 'Intuition, luck and misfortune in diabetes research', Diabetologia , 14, 353-58

Set clear limits before you begin, track outcomes without chasing losses, and celebrate small wins rather than aiming exclusively for jackpots

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Xiaohong W, Tao C, Sizhe C, Jie Z, Liangyu C, Changhao L, Yujie Z, Xiao W, Na L, Zhiyong M, Lei C, Qian L, Chenghu G, Qiming D, Wenqian Q, Yonghao H, Ruiqing R, Wenhai S, Haonan Z, Yun Z