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A study on diet-induced obese (DIO) mice demonstrated that a reduced-calorie diet combined with NNMT inhibition resulted in a unique microbiome composition, suggesting potential applications for 5-Amino-1MQ in gut microbiota-related metabolic research

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Dopamine release is also increased to a lesser degree, contributing to mild stimulant and reward effects, while serotonin levels are influenced only weakly

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