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Funding This study was supported by the Cross Discipline Project of First Hospital of Jilin University, China (JDYYJCHX2020001), Research and development of multi-targeted biomimetic exosome nanomaterials for primary liver cancer (20210204183YY) and the National Natural Science Foundation of China (32200977)

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Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease