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The Maf transcription factors: regulators of differentiation

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Recently, 6-hydroxymelatonin was seen to inhibit cytochrome C release from the mitochondria, suppress caspase 3 activity, and stabilize the mitochondrial membrane potential, thereby protecting against the neuronal cell death induced by oxygenglucoseserum deprivation in cultured cells [26,27,28,29]

3 Results 3.1 CB-839 treatment inhibits glutathione synthesis and the conversion of glutamine to glutamate in CLL cell lines Initially, we investigated CB-839s functional inhibition of GLS-1 ( Figures 1A, B )