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During such routine trips, the creatures get tested to determine the impact of the agencys operations on the local marine ecosystem

These data collectively demonstrate that: (i) doxorubicin is the principal cytotoxic driver, (ii) liposomal encapsulation enhances both DOX and BC bioactivity through improved uptake and controlled release, (iii) co-encapsulation preserves DOX potency (equivalent MTT IC) while amplifying downstream mechanistic endpoints, and (iv) the superior anticancer efficacy of BCDOX-Lipo arises from synergistic reinforcement of the G/S checkpoint coupled with sustained apoptotic commitment

doi: 10.1007/s10787-017-0323-6

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This version has two critical alterations: an extension of 13 amino acids at its N-terminus and, more importantly, the substitution of an Arginine for a Glutamic Acid at the third position