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Supplementing the medium with glutathione monoethyl ester in addition to AITC did not diminish the effect of AITC on root growth

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These data indicate that the disulfide bonds of both E127 ECD CQ211 ECL1 C and Q37 ECD CL379 ECL3 C are formed on the native protein in the absence of the antibody, strengthening the hypothesis that the current structure represents a physiologically relevant inactive conformation of GLP-1R

It has several important roles: Regulating blood glucose: GLP-1 increases insulin secretion and reduces glucagon levels, keeping blood sugar steady