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This, in turn, significantly upregulates Nrf2 and MITF expression, contributing to redox homeostasis and promoting melanocyte differentiation and migration [135]

J Clin Invest (2005) 115:11119

Karsdal, K

These results are significant in understanding the crosstalk within the gut-brain-kidney axis and offer therapeutic insights for managing neurological complications associated with CKD

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Additionally, TIGIT is expressed in terminally exhausted CD8 + T cell subsets, and when co-expressed with other co-inhibitory receptors, it directly suppresses T cell proliferation and function