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For the United States, the Institute of Medicine (IOM) has set a recommended dietary allowance (RDA) of 2.4 g/day for adults

Vitamin B12 is a key contributor to the bodys formation of cells, particularly in helping to create healthy red blood cells, and is now considered an essential piece of someones overall wellness regime

When B12 levels become problematic: High-dose supplementation (particularly doses exceeding 1,000 micrograms daily) Frequent B12 injections without medical supervision Underlying conditions affecting B12 metabolism Concurrent use of multiple B12-containing supplements The NHS does not set an upper safe limit for vitamin B12 because harmful effects from excessive intake have not been definitively established

Some historical reports describe improvements in anxiety, mood, sleep, and cravings, but evidence remains anecdotal

Oksenberg, A.B