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According to the Breakthrough Prize committee, these five scientists' complementary contributions from basic hormone discovery through physiological understanding to pharmaceutical development have led to highly effective drugs for diabetes and obesity, ushering in a new era of GLP-1 medicines for cardiometabolic disorders

Their effects on bowel transit lower in the gut appear more variable and may differ between individuals and medications

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We did not find any compensation in receptors from another GLP-1R-expressing site, 37, 38, 39 the NTS, in either sex or age

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