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In PCOS, it enhances insulin sensitivity, normalizes ovulatory function, and reduces ovarian oxidative damage (Yuan et al., 2025)

In addition to reducing protein disulfides, however, Trx1 and some Trx-family members, in particular the Trx-related protein of 14 kDa (TRP14), also participate in signaling by regulating protein- S- nitrosylation in NO-signaling and protein- S- persulfidation in H 2 S-signaling [114, 145, 149]

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(PubMed) Houghton SC, Eliassen AH, Zhang SM, et al

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