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The specific reactions users report most often: Compare this to actual GLP-1 receptor agonists, where nausea affects 20 to 44% of users, vomiting 5 to 24%, and constipation 12 to 24% across the STEP 1 and SURMOUNT-1 trial programs

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doi: 10.1016/j.molmet.2022.101533

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An increased risk of NAFLD (Non-alcoholic fatty liver disease) is seen in obese patients, with annual burdens in the treatment of NAFLD estimated to be in the hundreds of billions for the US [10]

However, these votes should not be interpreted as an immediate change in FDA policy or federal law