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Investigational New Drug Application (IND): If preclinical results are promising, the sponsor submits an IND application to the FDA, detailing the drug's composition, manufacturing, and proposed clinical trials

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For additional product-specific information on agents from the GLP-1 RA class, please refer to the companion lesson titled: An Overview of GLP-1 RAs: What Every Pharmacist Should Know. PUTTING IT ALL TOGETHER: CASE REVIEW AND DISCUSSION Case scenario JM is a 65-year-old man with T2D of 8 years duration

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Clinical trials have demonstrated average weight loss of approximately 15% with semaglutide 2.4 mg and up to 22% with tirzepatide 15 mg, though individual results vary considerably

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