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The highest concentration of 1MeTIQ (500 M) did not have a neuroprotective effect on the toxicity induced by MK-801 (Fig
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The mc4 receptor and control of appetite
Compared with mammals, fish have a lower ability to use carbohydrates as energy sources ( Reference Wilson 73 ) , but interactions between lipid and carbohydrate metabolism have been demonstrated in fish ( Reference Polakof, Mdale and Larroquet 74 , Reference Borges, Valente and Vron 75 )
However, given the safety or effectiveness concerns of anti-obesity drugs, many of the currently used drugs have limited clinical use