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In the CIA mouse model, resistance of TNF-induced synovial fibroblasts to ferroptosis can be eliminated by adding a low dose of IKE (20 mg/kg, twice a week) and a low dose of TNF inhibitor

The first is glutathione peroxidase (GPx) an enzyme family that the literature describes as a selenium-containing catalyst

Accordingly, SARS-CoV-2 hijacks several host proteases to enter human target cells and enhance its spread in the body

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(2022) The role of glutathione conjugation on the transcellular transport process of PEGylated liposomes across the blood brain barrier

10.1039/b710940g 71 MarquetteC