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DSIP administration has been reported in rodent models to attenuate stress-induced elevations of ACTH and corticosterone and to modify behavioral responses to acute stressors (Graf & Kastin, 1984)

Currently, WAKIX is the only therapy being studied for PWS patients with EDS, which affects approximately 50% of PWS patients

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This study describes EGL9 as a key dioxygenase for oxygen-dependent HIF prolyl hydroxylation in C

Circular RNA ACVR2A promotes the progression of hepatocellular carcinoma through mir-511-5p targeting PI3K-Akt signaling pathway

Given that TMCA can promote the GLP-1 production as a natural FXR antagonist 30 , we speculated that TMCA is a major contributor to the T3 effect on GLP-1 and insulin production and glucose homeostasis