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Most patients find that any initial discomfort is manageable and improves significantly after the first 12 weeks, with the therapeutic benefits becoming more apparent over the following months

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Non-enzymatic pathways are controlled by glutathione (GSH, ubiquitous in cells), uric acid, lipoic acid, NADPH, coenzyme Q, albumin, bilirubin, etc

Legro, MD, FACOG, can be reached at [email protected]

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