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Science 334 , 10811086 (2011)

Oxidative stress and ROS formation are markedly increased by uncontrolled hyperglycemia (2,6)

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Phentermine is chemically and pharmacologically related to the amphetamines and works as a sympathomimetic, increasing catecholamine signaling

Produces b-ions and y-ions Provides amino acid sequence information Enables localization of modifications Key Insight: Optimized fragmentation conditions are critical for complete sequence coverage

I can go online via the GP website and make an appointment for an eConsult but only a limited number are available each day, otherwise I must telephone and wait in a queue