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For example, Immunis Inc is developing IMM01-STEM for sarcopenic obesity 69 and Biophytis SA has progressed BIO101 (20-hydroxyecdysone) through a Phase I clinical trial 70 for age-related sarcopenia, including sarcopenic obesity

The inhibitory effect of BPC on extravasation in the lower dose (100 ng/kg) fell short of significance, but the higher, 10 g/kg dose of the peptide nearly completely abolished the extravasation induced by the 13-day ligature

However, challenges remain in this process

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Anemoside B4 attenuates nephrotoxicity of cisplatin without reducing anti-tumor activity of cisplatin

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