However, it would be scientifically inappropriate to attribute this progression directly to glutathione supplementation, as these patients had advanced chronic liver disease with a natural trajectory toward decompensation, and critically, there was no control group to compare against
The American Gastroenterological Association recommends against probiotic use in critically ill patients due to potential harm
Dependent on the substrate (amino acids, lipids, carbohydrates, iron) presented to the intestinal lumen, gut microbes can generate specific (aromatic) metabolites
Additionally, caloric restriction and altered fat intake patterns may further compromise gallbladder emptying
Some studies have observed that these small molecule inhibitors may promote inflammation and amplify NASH liver injury 47
10.1016/0893-133x(95)00137-3 73 MarkK