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pylori/atrophic gastritis, bariatric surgery, low dietary heme iron (vegetarian/vegan), elderly, high-dose/continuous PPI, concomitant metformin (B12), celiac/IBD all raise the chance that a PPI tips someone into anaemia

Amy Rothberg, a metabolism, nutrition, and diabetes expert at the University of Michigan, told Insider

Key differences: use, duration, and route The first practical difference is the intended length of treatment

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In support of this hypothesis, previous BRET experiments suggest that the distance between the two IGF1R intracellular domains increases in the presence of high concentrations of IGF1 27

Its novel dual action sets it apart from similar weight loss agents, addressing multiple facets of metabolic health simultaneously