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The bifunctional enzyme formimidoyltransferase cyclodeaminase (encoded by the FTCD gene) releases monoglutamate 5-forminino-THF from N -formimidoyl-L-glutamate (commonly referred to as FIGLU) and then glutamate and 5,10-methenyl-THF

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PATHWAYS: Inhibits TNF alpha [ 11 , 12 ] which is associated with Osteoporosis [ 187 ]

Semaglutide is a long-acting GLP-1 receptor agonist with 94% homology to native human GLP-1, engineered for once-weekly dosing and clinically validated for weight loss and type 2 diabetes