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Achieving and sustaining substantial weight loss is undeniably difficult in the post-industrial world, but the problems around prevention and secondary prevention of obesity and type 2 diabetes are not completely insurmountable for all if society decides to put genuine health promotion into action

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That is a substantial monotherapy effect for an appetite-axis-only agent, and it established cagrilintide as a credible weight-management candidate on its own

M.et al (2008)