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Many trials using the standardised extract of milk thistle support the clinical indications for both non-alcoholic and alcoholic fatty liver disease/damage as well as for cirrhosis, fatty liver, exposure to chemical pollutants (such as drugs, halogenated hydrocarbons, solvents, paints, glues and anaesthesia) and even for the treatment of death cap poisoning (1)
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This GI efficacy is pharmacologically separate from the pituitary GH-stimulating effect
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Nangaku M, Takama H, Ichikawa T et al (2023) Randomized, double-blind, placebo-controlled phase 3 study of bardoxolone methyl in patients with diabetic kidney disease: design and baseline characteristics of the AYAME study
Common Dose: Typically 100-200 mcg daily
