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One patient survived for 18 months without treatment [8] whereas another died a few months after total resection of a brain metastasis[9]

While the FDA-approved medications are administered via either an oral tablet or pre-filled pens, compounded versions of semaglutide have patients draw the dose themselves from vials, which can lead to dosing errors

Phase 1 (0.25 mg x 4 weeks) uses 1 mg total

Research has shown that semaglutide can reduce the risk of death from non-fatal heart attack or stroke by about 20%

Other GLP-1 medications contain different active ingredients, and some have an added component by mimicking another hormone called glucose-dependent insulinotropic polypeptide (GIP)

Brain Res (1998) 812(12):2569