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Generally, the answer is NO

43 In fact, MC1R activation in melanocytes themselves has been shown to activate antioxidant, DNA repair, and survival pathways

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The ToxDL server is devised for deep learning prediction of toxic domains in protein structures

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Mycotoxins such as ochratoxin, gliotoxin, and trichothecenes are known to: Disrupt lipid membranes Induce oxidative stress Alter immune signaling Affect central nervous system function In this case, both toxin burden and immune sensitization appeared to contribute to disease expression