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In the US, landmark initiatives such as the Orphan Drug Act (1983) 26 and the Accelerating Rare disease Cures program (2022) have promoted this mission by driving scientific innovation, regulatory flexibility and stakeholder engagement 27

Front Cell Infect Microbiol (2021) 11:663131

He XJ, Dai RX, Hu CL

Succinylation was assessed in IMAC phosphoproteome data using MSFragger-Labile in FragPipe, with PeptideProphet rescoring, PTMProphet localization (probability 0.75) and TMT-Integrator quantification

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