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Another study revealed that gentamycin induced nephrotoxicity by over-producing of reactive oxygen species and free radicals and significantly increased serum NGAL, KIM-1 and cystatin-c whereas Irbesartan and other angiotensin II blockers reverse this effect and improve renal function through Modulation of oxidative stress and endogenous antioxidant Capacity [57]

Both Cyp7a1 and Shp are target genes of the farnesoid X receptor (FXR)

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While the exact pathways are still being elucidated, several potential explanations have emerged

GLP-1 receptor agonists (GLP-1 RAs for short) are a class of drugs designed to mimic a natural hormone in the body known as glucagon-like peptide-1

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